You should take a look at http://guide.simutrans.com/
, there is a guide, that you can download (and read
First of all, after you start a new game try to find a COAL MINE and power plant. These two you should connect at first to start "moneymaker". This will provide you money for growing your network. If distance is small do use trucks. If there is a lot to travel with coal - use train.
Try to choose best locomotive (cheap and powerful) and use around 14 "coal wagons".
Another easy way to earn money is transporting oil to OIL POWER PLANT. Click on one do find out where are the OIL RIGS/PUMPS.
When you establish moneymaker route you can search for another routes. Try to connect rigs to chemical plants. Remember: some factories need more than one supplies to start a production.
And, last but not least, PASSENGERS.
Personally I search for a big city, build first BUS STOP in suburbs. Why? Later on it will be connected with TRAIN STATION. Try to cover whole city with some lines. Every line should have this specific BUS STOP in its schedule. This way in every city there is one BUS STOP treated like main station. Now you build TRAIN STATIONS joining this BUS STOP and hopefully earn more money.
Simutrans is really great, but you have to get used to it.