Windows 10 updates are a real pain in the posterior aren't they?! The Fall Creators Update (FCU; insert your own acronym!) completely trashed my hard disk, even converted it to RAW format - no I hadn't heard of it either. Anyway, to cut a very long and tedious story short I had to reinstall everything including Open TTD and I got the will-not-scroll-with-right-mouse-button problem which made it, if not unplayable, certainly unenjoyable. So, by way of experiment, I installed an older version of Open TTD (1.2.2) and it worked just fine. I'm not pointing the finger at Microsoft or the TTD community, I don't know enough about the minutia of these things to make any authoritative observation, but if you want a work-around this might be a way to go.
Hope this is helpful.
RAW Format is basically a partition (think of the disk like a big house or box and partitions are rooms or smaller boxes in a big box) with no formating other then tellling the computer the size of the partition and where its located. Seems weird that Windows 10 would do that but its possible that while updating the computer crashed, turned off, or a power outage happened (even a power surge that makes the lights flicker can cause comptures and electronics to shut off)
Also, make sure that after you install Windows 10, if your not getting any issues, use the "Run..." thingy or WIN KEY+R and type in "winver" to show a little window with what version of windows your running and what build.
It would seem that build 1709 is the true culprit here as perhaps they changed something up with how the mouse works and thus might cause issues with anything that relies on specifics of how the mouse drivers worked in Windows before WIndows 10 Build 1709. though I haven't heard of anything outside of OpenTTD with Windows 10 build 1709