Pixa is now released as 0.1 here
http://dev.openttdcoop.org/projects/pixa/repository
To get pixa, checkout (or download) that project, then from the project root run 'python setup.py install' (this will install pixa to your system python).
There's no further documentation and no tutorial yet. Pixa is in use for BANDIT and there are examples there.
If anyone would like to try using pixa, we can work through it here, which will provide an example / tutorial for others.
Pixa is good for three cases so far:
1. quickly generating sprites for vehicles or buildings that have regular shapes or patterns
2. compositing vehicle sprites with cargo sprites for different load states (empty, part-loaded, fully loaded etc).
3. recolouring; although recolour sprites can be used in game, an alternative approach is to recolour before compiling. This works for different cargos, liveries etc.
PIL is a required dependency; this is also required for nml, so many authors will already have it.
Pixa works well with python's built-in multi-processing module, which can significantly decrease render time when multiple thread units, cores or CPUs are available.
Pixa can be used with a makefile.
Pixa has also been tested as working on the openttdcoop compile farm.